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Ascherman syndrome or intrauterine synechiae is an intrauterine pathology that is characterized by the formation of numerous synechiae, resulting in the endometrium atrophying and sclerosing. The disease is named after D. Ascherman, a gynecologist who described and studied this pathology in detail. Due to the syndrome, the patient's menstrual cycle is disrupted and infertility develops. The syndrome is one of the most common causes of the development of uterine amenorrhea.


Causes of the syndrome

Infectious and traumatic agents, as well as neurovisceral causes, are considered factors contributing to the development of the disease. However, mechanical damage to the inner lining of the uterus is considered the most common cause. You can injure the endometrium during abortion, using intrauterine contraceptives and during diagnostic scraping of the uterine cavity. In addition, damage to the endometrium can uterine bleeding, polyps, myomectomy, metroplasty and cervical conization.

Intrauterine adhesions can develop against the background of genital tuberculosis. This diagnosis is usually confirmed by a biopsy of the endometrium of the uterus or a bacteriological study of menstrual blood. In addition, the endometrium may be badly affected by the drip introduction of solutions into the uterus, the passage of radiation therapy aimed at tumors of the reproductive organs. Frozen pregnancy can also cause the development of intrauterine adhesions.

Symptoms of intrauterine synechiae


  • Menstrual disorders of the type of algodismenorrhea (painful menstruation)
  • Violations of the menstrual cycle by type of hypomenorrhea (decrease in the volume of menstrual secretions), oligomenorrhea (decrease in the duration of menstruation).
  • Development of secondary amenorrhea (complete cessation of menstruation after a normally established menstrual cycle).
  • The hematometer (accumulation of menstrual secretions in the uterine cavity) develops when an overgrowth occurs in the lower part of the uterus if the endometrium continues to function normally in the upper part. Thus, menstrual blood cannot be released to the outside.
  • Habitual miscarriage of pregnancy with early termination.
  • Infertility.

In most cases, women have some kind of violation of the menstrual cycle, but sometimes there are no visible changes, and the pathology can be detected, for example, during a survey about infertility.

Treatment of Ascherman syndrome

Treatment involves dissection of adhesions in the course of operative hysteroscopy. After removing the adhesive process, the patient is prescribed hormone therapy, the purpose of which is to restore the function of the endometrium. If infectious diseases are detected, additional therapy with the use of antibiotics is performed.


Tashkent clinic Gatling-med, equipped with modern medical equipment and highly qualified gynecologists with significant experience, is ready to advise and conduct the necessary treatment at affordable prices and in the shortest possible time.