Peyronie's disease is a disease in which a dense fibrous plaque forms in the tunica albuginea of the penis. The disease is manifested by the occurrence of pain and curvature of the penis during erection. Often, such patients cannot live sexually. The formation of phimosis (an increase in the volume of scar tissue) in the tissues of the cavernous bodies is possible. This disease occurs in 30% of those affected by Peyronie's disease.
Erectile dysfunction, significant curvature of the penis, severe pain during intercourse - these are the complaints most often heard from patients. In total, Peyronie's disease affects about one percent of men.At the stage of inflammation, patients usually notice pain in the body of the penis. It can be observed at rest and intensify during an erection, as well as sexual intercourse. During this stage, the formation of "soft" plaques under the skin of the penis is also observed.The next stage in the development of Peyronie's disease is fibrotic. The clinical picture of this stage is characterized by the formation of a dense infiltrate under the skin of the penis, which may even be calcified.
As a rule, the characteristic clinical picture of the disease and the presence of an inflammatory process of the penis in the anamnesis do not leave questions about the diagnosis. For more accurate information about the number, location and structure of plaques, they resort to instrumental research methods. The results of ultrasound and radiography can become irreplaceable information when choosing the volume and method of surgery.
The disease lends itself to conservative and surgical treatment, which depends on the degree of the disease and the effectiveness of the previous procedures.The beginning of therapy is conservative. Reducing pain syndrome and visual changes, preventing the growth of fibrous plaques and degeneration of the tunica albuginea will allow the use of the prescribed by a specialist:
- vitamin E;
- electrophoresis with lidase
- electrophoresis with corticosteroid hormones.
Drug therapy, with all the frequency of use, is effective only in 30-60%, and if the drugs are injected directly into the plaques, only the aggravation of degenerative processes is likely. Each injection is another microtrauma, which causes the opposite effect and provokes further progression of the disease. As the scar tissue forms, any conservative treatment becomes less effective. In the same cases when calcium salts begin to be deposited in the plaque and bone tissue is formed, taking medications and physiotherapy procedures do not bring the desired effect and it becomes necessary to apply surgical methods.Surgical treatment of Peyron's disease is indicated in cases of significant deformity of the penis, which usually prevents intercourse and subsequently leads to erectile dysfunction. Surgical treatment is possible only when the fibrous plaques have stabilized, which means that the inflammatory phenomena have completely subsided and the curvature itself no longer progresses. The disappearance of the pain syndrome testifies to the stabilization of the process.
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